Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Gcna  germ cell nuclear acidic protein   (Synonyms: Gcna1, Gm52429)
Results	Reference
1*	J:89199 Adams IR, McLaren A, Identification and characterisation of mRif1: a mouse telomere-associated protein highly expressed in germ cells and embryo-derived pluripotent stem cells. Dev Dyn. 2004 Apr;229(4):733-44
1	J:339445 Ahmed AA, Salas E, Lanza DG, Heaney JD, Pangas SA, Generation of a novel Stra8-driven Cre recombinase strain for use in pre-meiotic germ cells in mice. Biol Reprod. 2023 Aug 10;109(2):184-191
1*	J:133516 Alton M, Lau MP, Villemure M, Taketo T, The behavior of the X- and Y-chromosomes in the oocyte during meiotic prophase in the B6.Y(TIR)sex-reversed mouse ovary. Reproduction. 2008 Feb;135(2):241-52
1	J:335514 Bird AD, Frost ER, Bagheri-Fam S, Croft BM, Ryan JM, Zhao L, Koopman P, Harley VR, Somatic FGFR2 is Required for Germ Cell Maintenance in the Mouse Ovary. Endocrinology. 2023 Mar 13;164(5)
1*	J:137617 Campagnolo L, Moscatelli I, Pellegrini M, Siracusa G, Stuhlmann H, Expression of EGFL7 in primordial germ cells and in adult ovaries and testes. Gene Expr Patterns. 2008 Jul;8(6):389-96
1	J:134687 Chang H, Gao F, Guillou F, Taketo MM, Huff V, Behringer RR, Wt1 negatively regulates {beta}-catenin signaling during testis development. Development. 2008 May;135(10):1875-85
1	J:112036 Costa Y, Speed RM, Gautier P, Semple CA, Maratou K, Turner JM, Cooke HJ, Mouse MAELSTROM: the link between meiotic silencing of unsynapsed chromatin and microRNA pathway?. Hum Mol Genet. 2006 Aug 1;15(15):2324-34
1	J:305426 Du G, Oatley MJ, Law NC, Robbins C, Wu X, Oatley JM, Proper timing of a quiescence period in precursor prospermatogonia is required for stem cell pool establishment in the male germline. Development. 2021 May 1;148(9):dev194571
1	J:265538 Fu A, Oberholtzer SM, Bagheri-Fam S, Rastetter RH, Holdreith C, Caceres VL, John SV, Shaw SA, Krentz KJ, Zhang X, Hui CC, Wilhelm D, Jorgensen JS, Dynamic expression patterns of Irx3 and Irx5 during germline nest breakdown and primordial follicle formation promote follicle survival in mouse ovaries. PLoS Genet. 2018 Aug;14(8):e1007488
1*	J:111787 Gao F, Maiti S, Alam N, Zhang Z, Deng JM, Behringer RR, Lecureuil C, Guillou F, Huff V, The Wilms tumor gene, Wt1, is required for Sox9 expression and maintenance of tubular architecture in the developing testis. Proc Natl Acad Sci U S A. 2006 Aug 8;103(32):11987-92
1*	J:290712 Ishiguro KI, Matsuura K, Tani N, Takeda N, Usuki S, Yamane M, Sugimoto M, Fujimura S, Hosokawa M, Chuma S, Ko MSH, Araki K, Niwa H, MEIOSIN Directs the Switch from Mitosis to Meiosis in Mammalian Germ Cells. Dev Cell. 2020 Feb 24;52(4):429-445.e10
1	J:316818 Ito T, Osada A, Ohta M, Yokota K, Nishiyama A, Niikura Y, Tamura T, Sekita Y, Kimura T, SWI/SNF chromatin remodeling complex is required for initiation of sex-dependent differentiation in mouse germline. Sci Rep. 2021 Dec 15;11(1):24074
1*	J:215225 Koubova J, Hu YC, Bhattacharyya T, Soh YQ, Gill ME, Goodheart ML, Hogarth CA, Griswold MD, Page DC, Retinoic acid activates two pathways required for meiosis in mice. PLoS Genet. 2014 Aug;10(8):e1004541
1	J:175257 Krentz AD, Murphy MW, Sarver AL, Griswold MD, Bardwell VJ, Zarkower D, DMRT1 promotes oogenesis by transcriptional activation of Stra8 in the mammalian fetal ovary. Dev Biol. 2011 Aug 1;356(1):63-70
1	J:128313 Lei N, Hornbaker KI, Rice DA, Karpova T, Agbor VA, Heckert LL, Sex-specific differences in mouse DMRT1 expression are both cell type- and stage-dependent during gonad development. Biol Reprod. 2007 Sep;77(3):466-75
1*	J:104848 Lin Y, Page DC, Dazl deficiency leads to embryonic arrest of germ cell development in XY C57BL/6 mice. Dev Biol. 2005 Dec 15;288(2):309-16
1	J:194288 Manosalva I, Gonzalez A, Kageyama R, Hes1 in the somatic cells of the murine ovary is necessary for oocyte survival and maturation. Dev Biol. 2013 Mar 15;375(2):140-51
1	J:83934 McClellan KA, Gosden R, Taketo T, Continuous loss of oocytes throughout meiotic prophase in the normal mouse ovary. Dev Biol. 2003 Jun 15;258(2):334-48
1	J:145458 Memon MA, Anway MD, Covert TR, Uzumcu M, Skinner MK, Transforming growth factor beta (TGFbeta1, TGFbeta2 and TGFbeta3) null-mutant phenotypes in embryonic gonadal development. Mol Cell Endocrinol. 2008 Nov 6;294(1-2):70-80
1	J:184928 Miles DC, van den Bergen JA, Wakeling SI, Anderson RB, Sinclair AH, Western PS, The proto-oncogene Ret is required for male foetal germ cell survival. Dev Biol. 2012 May 1;365(1):101-9
1	J:306151 Nguyen DH, Soygur B, Peng SP, Malki S, Hu G, Laird DJ, Apoptosis in the fetal testis eliminates developmentally defective germ cell clones. Nat Cell Biol. 2020 Dec;22(12):1423-1435
1	J:281436 Nicol B, Grimm SA, Chalmel F, Lecluze E, Pannetier M, Pailhoux E, Dupin-De-Beyssat E, Guiguen Y, Capel B, Yao HH, RUNX1 maintains the identity of the fetal ovary through an interplay with FOXL2. Nat Commun. 2019 Nov 11;10(1):5116
1	J:232363 Park E, Lee B, Clurman BE, Lee K, NUP50 is necessary for the survival of primordial germ cells in mouse embryos. Reproduction. 2016 Jan;151(1):51-8
1*	J:111998 Reinholdt LG, Munroe RJ, Kamdar S, Schimenti JC, The mouse gcd2 mutation causes primordial germ cell depletion. Mech Dev. 2006 Jul;123(7):559-69
1*	J:326811 Rodriguez KF, Brown PR, Amato CM, Nicol B, Liu CF, Xu X, Yao HH, Somatic cell fate maintenance in mouse fetal testes via autocrine/paracrine action of AMH and activin B. Nat Commun. 2022 Jul 15;13(1):4130
1	J:63161 Rucker EB 3rd, Dierisseau P, Wagner KU, Garrett L, Wynshaw-Boris A, Flaws JA, Hennighausen L, Bcl-x and Bax regulate mouse primordial germ cell survival and apoptosis during embryogenesis. Mol Endocrinol. 2000 Jul;14(7):1038-52
1	J:334500 Ruthig VA, Yokonishi T, Friedersdorf MB, Batchvarova S, Hardy J, Garness JA, Keene JD, Capel B, A transgenic DND1GFP fusion allele reports in vivo expression and RNA-binding targets in undifferentiated mouse germ cells. Biol Reprod. 2021 Apr 1;104(4):861-874
1	J:205334 Saba R, Kato Y, Saga Y, NANOS2 promotes male germ cell development independent of meiosis suppression. Dev Biol. 2014 Jan 1;385(1):32-40
1*	J:209131 Saba R, Wu Q, Saga Y, CYP26B1 promotes male germ cell differentiation by suppressing STRA8-dependent meiotic and STRA8-independent mitotic pathways. Dev Biol. 2014 May 15;389(2):173-81
1	J:217384 Suzuki A, Niimi Y, Saga Y, Interaction of NANOS2 and NANOS3 with different components of the CNOT complex may contribute to the functional differences in mouse male germ cells. Biol Open. 2014;3(12):1207-16
1	J:187029 Suzuki A, Saba R, Miyoshi K, Morita Y, Saga Y, Interaction between NANOS2 and the CCR4-NOT deadenylation complex is essential for male germ cell development in mouse. PLoS One. 2012;7(3):e33558
1	J:263202 Ungewitter EK, Rotgers E, Kang HS, Lichti-Kaiser K, Li L, Grimm SA, Jetten AM, Yao HH, Loss of Glis3 causes dysregulation of retrotransposon silencing and germ cell demise in fetal mouse testis. Sci Rep. 2018 Jun 25;8(1):9662
1	J:32051 Wang D, Enders GC, Expression of a specific mouse germ cell nuclear antigen (GCNA1) by early embryonic testicular teratoma cells in 129/Sv-Sl/+ mice. Cancer Lett. 1996 Feb 27;100(1-2):31-6
1*	J:85108 Wong JC, Alon N, Mckerlie C, Huang JR, Meyn MS, Buchwald M, Targeted disruption of exons 1 to 6 of the Fanconi Anemia group A gene leads to growth retardation, strain-specific microphthalmia, meiotic defects and primordial germ cell hypoplasia. Hum Mol Genet. 2003 Aug 15;12(16):2063-76
1	J:237277 Wu Q, Fukuda K, Kato Y, Zhou Z, Deng CX, Saga Y, Sexual Fate Change of XX Germ Cells Caused by the Deletion of SMAD4 and STRA8 Independent of Somatic Sex Reprogramming. PLoS Biol. 2016 Sep;14(9):e1002553
1*	J:233398 Wu RC, Zeng Y, Pan IW, Wu MY, Androgen Receptor Coactivator ARID4B Is Required for the Function of Sertoli Cells in Spermatogenesis. Mol Endocrinol. 2015 Sep;29(9):1334-46